Optimal vaccine allocation for COVID-19: the critical role of single-dose vaccination.
Optimal vaccine allocation for COVID-19: Who should get vaccinated first?
In collaboration with Tiffany Leung, Julie Eaton and Elizabeth R. Brown, we are investigating the optimal allocation strategies for COVID-19 vaccines (accepted, Science Advances). Our pre-print is available here!
The New York Times magazine did a really nice piece covering our work here!
Undark magazine has an excellent piece covering our work here!
COVID-19 dynamics and social distancing interventions
What does the term “flattening the curve” exactly mean? In this paper, Tiffany Leung and I quantified the effectiveness of social distancing interventions against COVID-19. We showed that if started early, social distancing interventions delay the epidemic, and if started late, they result in flattening the curve. https://wwwnc.cdc.gov/eid/article/26/8/20-1093_article
Listen to a podcast about this work here:
Optimizing cholera vaccine allocation
What is the best use of scarce resources during a cholera outbreak? How is the optimal use of vaccine depend on things like transmissibility, age, setting (urban vs. rural)? These are some of the questions we are currently tackling under a Wellcome Trust grant.
How do B-cells differentiate to create antibodies against virtually every single antigen they encounter? In collaboration with Ollivier Hyrien, we are developing a stochastic model of B-cell affinity maturation.